Current Issue : October-December Volume : 2018 Issue Number : 4 Articles : 7 Articles
Ganoderma lucidum is a type of fungus which grows on dead and deciduous trees. Ganoderma lucidum has a vast history of utilization as a supplement for propelling life span and the advancement of a healthier life in Asian region i.e. in China, Japan and Korea. All Traditional Chinese Medicine specialists believe that Ganoderma lucidum is the most highlighted one amongst the most powerful available adaptogens. Adaptogens are the herbal supplements that have capability of developing the body's impenetrability to stress and offer some assistance with defeating all the troubles and difficulties which are against health and this process is done in the most rapid and fast fashion. Ganoderma products are widely spread in America in the latest couple of years, practically as they have been surely believed and utilized in traditional medicine system of China for an extensive period....
The present study was aimed to determine the effect of methanolic extract of S. torvum on isolated strip ileum of overnight fasted rat. S. torvum seeds were extracted with methanol by soxhlet extraction. Cumulative dose response of acetylcholine was taken on student organ bath with a constant dose of S. torvum methanolic extract (STME) 0.4 ml (100 mg/ml). pA2 value was calculated by Schild plot method, then compared with control and treated isolated tissue responses. Methanolic extract increases the contractility of rat ileum as compared to the control rat ileum tissue preparation, therefore pA2 value of atropine on treated tissue is less as compared to pA2 value on control tissue.pA2 value on treated tissue is 7.88 and pA2 value on control tissue is 8.2. From the following results, it was concluded that extract acts as agonist which increases contractile effect of smooth muscle of ileum....
Complication of diabetes mellitus induces cognitive impairments and functional change in brain. The main objective of this study was to evaluate the effect of methanolic extract of S. torvum extract on behavioral indices in alloxan induced diabetic rats. The behavioral effect of S. torvum in alloxan induced diabetic rats were evaluated and compared with diabetic control group (alloxan 120 mg/kg) using object recognition test, grip strength test and actophotometer. Results of the present study was evaluated by one way ANOVA followed by Dunnett’s test and expressed in mean±SEM. Diabetic rats treated with S. torvum (100 mg/kg) and with metformin (120 mg/kg) showed significant increase in discrimination index as compared to diabetic rats in object recognition test, significantly (p<0.05) increased muscle strength and locomotor activity which was measured by digital grip strength meter and actophotometer respectively....
The various extracts of Tradescantia spathacea were investigated for its anti-arthritic activity in male albino rats. Freund’s adjuvant induced arthritis model was applied for the evaluation of anti-arthritic activity. Dexamethasone (0.1 mg/kg) was used as a regular drug. The ethanolic extract of T. spathacea exhibited significant anti-arthritic activity. The doses of 150 and 300 mg/kg of the ethanolic extract of T. spathacea, biochemical parameters assayed were rheumatoid factor, C-reactive protein (CRP), superoxide dismutase (SOD), catalase (CAT). The ethanol extract at the dose of 300 mg/kg body weight inhibited the rat paw edema, which is comparable with standard drug dexamethasone, inhibition of rat paw edema after 21 days. The results of the present investigation concluded, ethanol extract of T. spathacea possess a significant anti-arthritic activity against adjuvant induced arthritis and justifying its therapeutic role in arthritic condition....
Both plants Ventilago maderspatana Gaertn. and Ziziphus xylopyrus (Retz) Willd. were utilized for cough and cold treatment in Titupati district of Andhra Pradesh, India. This study was aimed at investigating anti-asthmatic property of aqueous and ethanolic extracts of stem of Ventilago maderspatana Gaertn and stembark of Ziziphus xylopyrus (Retz) Willd. obtained by maceration and extraction. Preliminary phytochemical analysis was carried out for all extracts. Both plants were found to contain different phytoconstituents such as alkaloids, glycosides, steroids and sterols, saponins, flavonoids, carbohydrates and tri-terpenoids and showed the absence of amino acids, proteins and acidic compounds. Acute toxicity studies were carried out and the extracts were found to be safe till 2000 mg/kg b.w. in female balb/c mice. 1/10th and 1/20th dose were selected as per OECD (423). In-vivo anti-asthmatic studies were carried out in ova albumin induced asthmatic animal model. Histo-pathological study on lung tissue was carried out. The study justified the use of stem of Ventilago maderspatana Gaertn and stem bark of Ziziphus xylopyrus (Retz) Willd. in the management of asthma in Indian folk medicine. It was determined from the stem of Ventilago maderspatana Gaertn stem bark of Z. xylopyrus (Retz) Willd. for the first time....
The present study evaluates nootropic activity of Solanum torvum in mice. Y-maze, T-maze, open field apparatus, novel object recognition test apparatus are some of the behavioral models which were used to evaluate various parameters such as number of arm entries and percent alterations, locomotor activity, grooming, rearing behavior and discrimination index respectively. The animals were divided into different groups and received different doses of S. torvum methanolic extract (STME-30 mg/kg and 100 mg/kg) and its isoflavonoid rich fraction (IRF-10 mg/kg and 30 mg/kg). S. torvum extract and fraction were combined with sildenafil (8 mg/kg). All the treatment groups were compared with control group. Results were analyzed using a one-way ANOVA followed by a Dunnett’s test and expressed as mean±SEM. A significant increase in percentage alteration in T-maze and Y-maze was observed, whereas open field tests revealed a significant reduction in rearing and grooming behaviors at all doses tested while no significant changes in horizontal locomotion were seen. An increase in discrimination index (D) was observed in novel object recognition test. The experimental results demonstrate that the doses of STME and its IRF in combination with sildenafil possess significant nootropic activity....
Cancer has become the most important cause of death in many countries. Cancer is the uncontrolled growth of abnormal cells in the body. Cancerous cells are also called malignant cells. Human papilloma virus were shown to be associated with elevated risks of stomach, liver and cervical cancer, respectively. Tobacco smoking was shown to be extensively allied with higher lung cancer risk and reasonably augmented all cancer risk. Unnecessary alcohol drinking appears to augment the risk of colorectal cancer. Betel nut chewing was allied with privileged risk of oral and esophageal Cancer. Nowadays Breast cancer is also the leading cause of cancer death among females. Cancer prevention requires smoking cessation, increased ingestion of fruits and vegetables, moderate use of alcohol, caloric restriction, exercise, averting of direct exposure to sunlight, arsenic, radon, asbestos, minimal meat consumption, use of whole grains, use of vaccinations and regular check-up. We review the causes, different forms and the effect of herbal extracts for cancer....
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